Swiss chronometer-maker, established in Paris.
He was at the head of the workshop belonging to his uncle, Ferdinand Berthoud, later succeeding him.
A specialist in precision timepieces, he made marine and pocket chronometers, astronomical clocks and watches.
In 1802 he was granted the position of Horologist to the Navy then, in 1805, Horologist to the Observatory and the Board of Longitude in Paris.
A member of the French Academy of Science, he is the author of a book of "conversations" on naval timekeeping: Entretiens sur l’Horlogerie à l’Usage de la Marine (1812).